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Search Result For 'hepatocellular carcinoma' , Result Number : 42

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Mabrouk Ibrahim Mohamed Ismail
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Combination of Alpha-1-Acid Glycoprotein and Alpha Fetoprotein as an Improved Diagnostic Tool for Hepatocellular Carcinoma
Fatma Desouky Mohamed Abdallah
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Zagazig Veterinary Journal, ©Faculty of Veterinay Medicine, Zagazig University, 44511, Egypt. Volume 47, Number 2, p. XXX, June 2019 DOI: 10.21608/zvjz.2019.11121.1034 RSEARCH ARTICLE Application of Different Biostatistical Methods in Biological Data Analysis Khairy M. El-Bayomi, Fatma D. Mohamed, Mahmoud S. El-Tarabany and Hagar F. Gouda* Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt Abstract Logistic regression is one of the popular methods used in genetic data analysis. That is applied to predict a categorical binary dependent variable on basis of predictor variables, and to test the probability of getting a particular value of the dependent variable that is related to the explanatory variable. The objective of this study is to highlight the crucial role of biostatistical methods in increasing the accuracy of the results in veterinary and biological practices. Statistical analysis of previously published data in the National Research Center, Dokki, Giza, Cairo, Egypt was done using SPSS version, 24 to predict hepatocellular carcinoma metastasis by knowing the genotypes, age, and gender of the patients. The genotypes and gender displayed a significant effect on metastasis (P < 0.05) while age had no significant effect on metastasis (P > 0.05). There are other types of data (animal breeding and production) which were analyzed by repeated measures ANOVA and principal component analysis (PCA). The repeated measures ANOVA is equivalent to normalized ANOVA, but for related, not independent groups. Data of this test was obtained from a study aimed to measure body weight of three breeds of rabbits at 4 time points 4th, 6th, 8th and 10th weeks of the experiment. The main effect of breed types of rabbits was significant (P < 0.05), the time (weeks) was highly significant (P < 0.001) and their interaction was also highly significant (P < 0.001). Principal component analysis (PCA) is used to reduce a large set of variables to a small set that still contains most of the information in the large set. A reduced set is easier to analyze and interpret. Data with 6 variables reduced to only 2 variables where initial eigenvalues were > 1 for two variables and their values were (2.768 and 1.147).
Mostafa Khamies Sultan Farag
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
11. Design, Synthesis, Molecular Modeling and Biological Evaluation of Novel Substituted Pyrimidine Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma
Ashraf Khaliefa Ashraf Elnagar
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The relationship between hepatitis C - related hepatocellular carcinoma and IL-23 receptor gene polymorphism
Ayman Mohamed Abdou
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Residual hepatitis C virus in peripheral blood mononuclear cell as a risk factor for hepatocellular carcinoma after achieving a sustained virological response: a dogma or fiction.
Ahmed Mohamed Algebaly Ahmed Kammil
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
the efficacy of using neutrophil to lymphocyte ratio and interleukin 6 as predictors of interventional treatment of hepatocellular carcinoma
Osama Mohamed Hamed Khalil
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The Diagnostic Value of Arginase-1, FTCD, and MOC-31 Expression in Early Detection of Hepatocellular Carcinoma (HCC) and in Differentiation Between HCC and Metastatic Adenocarcinoma to the Liver
Ayman Fathy Elsayed Mohamed Badran
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
hepatocellular carcinoma
Besheer Mohamed Helmy Mahdy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Hepatocellular carcinoma
Taghreed Mohamed Abdallah Mahmud
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Thrombophilia in hepatocellular carcinoma
Tayseer Refaat Ibrahim Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The utility of immunohistochemical expression of glypican-3 (GPC3) and enhancer of zeste homologue-2 (EZH2) protein in the diagnosis of liver nodules Samah S. Elbasateeny and Taiseer R. Ibrahim Abstract Aim: The aim of this study was to examine the immunohistochemical expression of glypican-3 (GPC3) and enhancer of zeste homologue-2 (EZH2) in various histological types of hepatic nodules to investigate their discriminatory diagnostic value between primary malignant, metastatic and non malignant nodules. Materials and methods We correlated markers’ expression with the clinicopathological variables of primary liver malignancy. Markers’ expression was analyzed in 82 liver true-cut needle biopsies; 59.76% were primary liver malignancies, 15.85% were metastatic carcinomas, and 24.39% were nonmalignant nodules. Results GPC3 expression was detected in 84.37 and 17.64% of hepatocellular carcinomas (HCC) and cholangiocarcinomas (CC), respectively, but was not expressed in any of the metastatic nodules. In HCC, GPC3 was expressed more with cirrhosis, with large masses of tumor and with high HCC grades with statistically significant differences (P= 0.036, 0.024, and 0.030, respectively). EZH2 expression was detected in 90.62% of HCCs, in all cases of CC and metastatic nodules, and in 5% of nonmalignant nodules. The sensitivity, specificity, and diagnostic accuracy of differentiating HCCs from nonmalignant nodules were 84.38, 100, and 90.38%, respectively, for GPC3, and 90.63, 95, and 92.31%, respectively, for EZH2. The sensitivity, specificity, and diagnostic accuracy for differentiating HCCs from CCs were 84.38, 82.35, and 83.67%, respectively, for GPC3, and 90.63, 0.0, and 59.18%, respectively, for EZH2. The sensitivity, specificity, and diagnostic accuracy for differentiating HCCs from metastatic nodules were 84.38, 100, and 88.89%, respectively, for GPC3, and 90.63, 0.0, and 64.44%, respectively, for EZH2. Conclusion GPC3 can be used as a first-line marker for differential diagnoses of HCCs from nonmalignant nodules, CCs, and metastases (accuracy rate: 90.38, 83.67, and 88.89%, respectively). In HCC, overexpression of GPC3 is associated with poor prognostic factors such as large tumor size and high tumor grade. EZH2 is a reliable marker for HCCs compared with nonmalignant nodules (accuracy rate: 92.31%). However, EZH2 is not specific for HCC as all other examined hepatic malignancies were positive as well.
Hanan Lotfy Mohamed Elsayed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Diagnostic role of Arginase 1,MOC31 and CDX2 in the Differentiation of hepatocellular carcinoma,cholangiocarcinoma and metastatic colonic carcinoma of the liver
Sameh Mahmoud Abdelmoneim Mahmud
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Combined percutaneous ethanol injection and mitoxantrone versus radiofrequency ablation in the treatment of hepatocellular carcinoma
Sameh Mahmoud Abdelmoneim Mahmud
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Dickkopf-1: As a Diagnostic and Prognostic Serum Marker for Hepatocellular Carcinoma
Sameh Mahmoud Abdelmoneim Mahmud
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Efficacy of Using Neutrophil to Lymphocyte Ratio and Interleukin 6 as Outcome Predictors of Interventional Treatment of Hepatocellular Carcinoma
Samar Mahmoud Abdelhalim Mustafa
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
EFFECT OF SINGLE NEOCLEOTIDE POLYMORPHISM OF RECK GENE PROMOTER ON HEPATOCELLULAR CARCINOMA: IN CORRELATION WITH CLINICAL AND LABORATORY PARAMETERS. Nahla I. Elattar1, Samar M. Sharaf1, Afify F. Afify2 and Reem M. Allam1,*. 1. Clinical Pathology Faculty of Medicine, Zagazig University, Egypt. 2. Internal Medicine Departments, Faculty of Medicine, Zagazig University, Egypt.nt. J. Adv. Res. 4(10), 561-567
Sharweet Mahmoud Ibrahim Ahmmid
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Association of Circulatory Long Non-Coding RNA AFAP1-AS1 with Risk and Progression of Hepatocellular Carcinoma in Egyptian Patients with Chronic Hepatitis C Virus Infection
Sharweet Mahmoud Ibrahim Ahmmid
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
The Association of Serum Estradiol Level with the Susceptibility and Clinicopathological Features of Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease
Shereen Mostafa Saleh Elshorbagy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Evaluation of the response to Leuprolide acetate ( Lupron Depot- 3 month 11.25 mg) (GHRH agonist) in primary Hepatocellular carcinoma and its relation to Androgen receptor).
Safaa Mahmoud Mohamed Alllwy
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Microrna-150 and microrna-101as diagnostic markers for hepatitis B virus related hepatocellular carcinoma in Egypt
Abeer Mohamed Abdelaziz Nafea
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Clinical significance of serum clusterin as a biomarker for evaluating diagnosis and metastasis potential of viral- related hepatocellular carcinoma الأهمية السريرية للكلستيرين في المصل كمؤشر بيولوجي لتقييم تشخيص وإمكانية حدوث نمو ثانوي لسرطان الكبد بحث مقبول للنشر في مجلة الكيمياء الإكلينيكية – 23 ابريل 2012 (With Impact Factor 2.02)
Abeer Mohamed Abdelaziz Nafea
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Corroboration of Serum Apolipoprotein J (Clusterin) as a Biomarker for Evaluating Hepatocellular Carcinoma ا التأكد من أبو ليبوبروتين جي (كلستيرين) في المصل كمؤشر بيولوجي لتقييم سرطان الكبد بحث منفرد منشور في المجلة الأفريقية المصرية للأمراض المعدية والمتوطنة- المجلد (2) العدد (1) مارس 2012
Essam Abdelwahab Abdelwahab
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Association of genetic polymorphism of BCL-2 (rs2279115) with susceptibility to HCV-related hepatocellular carcinoma
Essam Abdelwahab Abdelwahab
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Genetic polymorphism of IL-23R influences susceptibility to HCV-related hepatocellular carcinoma
Alaaeldeen Ahmed Mohamed Faraj
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Association of thrombogenic gene polymorphisms with hepatocellular carcinoma in HCV Egyptian patients
Emad Abdelhamied Mostafa Ahmed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
treatment of hepatocellular carcinoma
Maher Boraie Mohammed Boraie
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Value of Regulatory T Cell in Hepatocellular Carcinoma Patients
Mohamed Mahmoud Abdel Aal Sallam
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Aspartate Aminotransferase To Platelet Ratio Index Versus Neutrophil To Lymphocyte Ratio For Prediction Of Post Radiofrequency Ablation Recurrence Of Hepatocellular Carcinoma.
Nearmeen Mohammed Rashad Ahmmad
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Serum miRNA-27a and miRNA-18b as potential predictive biomarkers of hepatitis C virus-associated hepatocellular carcinoma
Halle Massad Yusuf
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Possible Relationship between Matrix Metalloproteinases Genotyping and Risk of Hepatocellular Carcinoma in HCV Infected Patients
Hany Mohamed Sadiq Musa
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
hepatocellular carcinoma
Heba Fekry Abdel Majid Taha
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
hepatocellular carcinoma
Huda Abdeen ebrahim
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Clinical value of fetuin A in cirrhosis associated hepatocellular carcinoma
Waseem Mohammed Saleem Ahmed
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Residual hepatitis C virus in peripheral blood mononuclear cell as a risk factor for hepatocellular carcinoma after achieving a sustained virological response: a dogma or fiction
Marwan Mohammed Nabil Mohammed Gohary
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Lipocalin-2: A novel diagnostic marker for hepatocellular carcinoma
Asmaa Ibrahim Abdelwahab
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
expression of survivin in HBV, HCV and hepatocellular carcinoma, a comparative study
Amal Fawzy AbdelHamid Hassan
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
apelin gene polymorphism in hepatocellular carcinoma associated with chronic hepatitis c infection
Marwa Mohammed Ayesh Othman Hashim
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
hepatocellular carcinoma and HCV
Mohamed Hesham Saleh Saleh Radwan
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
18F FDG-PET/CT IN ASSESSMENT OF INTERVENTIONALLY TREATED HEPATOCELLULAR CARCINOMA (HCC) PATIENTS
Amgad Mahmood El Sayed Ahmed Ibrahim Sheikh
- Faculty Research Area On Zu Site
Transarterial chemoembolization(TACE) in treatment of non-resectable hepatocellular carcinoma: comparative study between conventional TACE and drug eluting bead TACE
- Faculty Research Area On Zu Site
- Faculty Research Area On Staff Site
Golgi Protein 73: as a diagnostic and prognostic marker for hepatocellular carcinoma
Hoda fathy mohamed
- Faculty Research Area On Zu Site
Prognostic Significance of VEGF and HIF-1 α in Hepatocellular Carcinoma Patients Receiving Sorafenib Versus Metformin Sorafenib Combination